Neuromuscular block

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منابع مشابه

Neuromuscular block.

Descriptions of the South American arrow poisons known as curares were reported by explorers in the 16th century, and their site of action in producing neuromuscular block was determined by Claude Bernard in the mid-19th century. Tubocurarine, the most important curare alkaloid, played a large part in experiments to determine the role of acetylcholine in neuromuscular transmission, but it was n...

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Mivacurium-induced prolonged neuromuscular block.

We report a case of prolonged neuromuscular block after administration of mivacurium 0.2 mg kg-1 to a 16-yr-old patient where the duration of block was 2.5 h. The interesting points in this case were that the patient had homozygous atypical plasma cholinesterase deficiency (both parents had a normal phenotype) following liver transplantation. Investigations showed low plasma cholinesterase acti...

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Monitoring neuromuscular block: an update.

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Automatic control of neuromuscular block with atracurium.

We have developed and tested a system for providing automatic control of neuromuscular block with atracurium. The degree of neuromuscular block was monitored in the small muscles of the hand using a Datex Relaxograph, and the signal was used as the controlled variable for a proportional plus integral controller. A preloaded integral was used to shorten the period of stabilization. The system wa...

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ژورنال

عنوان ژورنال: British Journal of Pharmacology

سال: 2006

ISSN: 0007-1188

DOI: 10.1038/sj.bjp.0706404